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Pittsburgh head coach Mike Tomlin moved to 1-0 against the 49ers for his career with that 2007 outcome, while Harbaugh will be facing both the Steelers and Tomlin for the first time in his present position.
Even if Roethlisberger (3526 passing yards, 21 TD, 11 INT) does manage to play, the Steelers' offensive game plan will probably be altered somewhat because of his reduced mobility. Normally a team that likes to stretch the field with its pairing of fleet-footed wide receivers Mike Wallace (62 receptions, 1034 yards, 8 TD) and Brown (55 receptions, 925 yards, 2 TD), both of whom are averaging over 16 yards a catch this season, Pittsburgh may decide to lean more on running backs Rashard Mendenhall (710 rushing yards, 8 TD, 13 receptions) and Isaac Redman (353 rushing yards, 1 TD, 14 receptions) in this one. It's not the desired strategy, however, as lead back Mendenhall has had a disappointing year after posting career bests of 1,273 rushing yards and 13 touchdowns in 2010, having recorded just one 100-yard effort while working behind a shuffled front line that's dealt with injuries throughout the season. One of those occurred in the Cleveland game, with standout center Maurkice Pouncey incurring an ankle sprain of his own that his status up in the air as well for Monday. The 37- year-old Batch has attempted just 53 passes over the past three years, but did make a pair of starts in place of a suspended Roethlisberger last season and threw for three touchdowns in a win at Tampa Bay in one of those assignments.
WHEN THE 49ERS HAVE THE BALL
Pittsburgh's tradition of excellent defense has continued during this 2011 season, and esteemed coordinator Dick LeBeau's group seems to have raised its play to an even higher level recently. The Steelers have allowed a scant 19 total points and only one touchdown over their last three wins and forced eight turnovers over that span, rectifying what had been a sore spot for the club early on this year. A secondary headlined by 2010 NFL Defensive Player of the Year Troy Polamalu (76 tackles, 1 sack, 1 INT), fellow safety Ryan Clark (86 tackles, 1 INT) and shutdown cornerback Ike Taylor (37 tackles, 2 INT, 11 PD) has been very stout, as Pittsburgh has surrendered the fewest passing yards (179.1 ypg) in the league despite both Woodley (37 tackles, 9 sacks, 1 INT) and Harrison missing extensive time. Woodley is due back this week from his hamstring injury and was on a roll prior to getting hurt in late October, racking up 7 1/2 sacks in just four games before being shelved, while second- year outside linebacker Jason Worilds (26 tackles, 3 sacks) is coming off a two-sack outburst against the Browns in his place. The Steelers have held their own against the run as well, with Polamalu, inside linebacker Lawrence Timmons (70 tackles, 1 INT) and unheralded end Brett Keisel (41 tackles, 3 sacks) spearheading a corps that's kept eight of 13 opponents under 100 rushing yards.
KEYS TO THE GAME
Pittsburgh is going to have to rely on its defense whether or not Roethlisberger suits up, and how the AFC powerhouses perform on that side of the ball is often an indicator of their success. The Steelers are 9-0 when giving up 306 total yards or less this season, and the 49ers average only a shade above that number on offense for the year.
OVERALL ANALYSIS
Sportsbook Betting Lines Predicted Outcome: Steelers 20, 49ers 16
On the Bears' second possession of the game, Knox caught a 17-yard pass over the middle of the field. Knox then lost control of the football and a scramble for the ball followed.
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Percent Shooting Goal Efficiency Wrap Salvage On Points
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